Fig. 7: Protein expression correlation analyzes among GAB1, RNF220, Smurf1, and Smurf2 in human clinical medulloblastoma samples. | Cell Death & Disease

Fig. 7: Protein expression correlation analyzes among GAB1, RNF220, Smurf1, and Smurf2 in human clinical medulloblastoma samples.

From: Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma

Fig. 7: Protein expression correlation analyzes among GAB1, RNF220, Smurf1, and Smurf2 in human clinical medulloblastoma samples.

A Representative immunohistochemical images of clinical Shh- and non-Shh medulloblastoma samples with the indicated antibodies. Scale bar, 5 mm. B–G Statistical analysis of the correlation among GAB1-RNF220 (B), Smurf1-RNF220 (C), Smurf2-RNF220 (D), Smurf1-Smurf2 (E), Smurf1-GAB1 (F), and Smurf2-GAB1 (G) based on the immunohistochemical scores, Pearson product-moment correlation coefficient analysis was used for the statistics. MB medulloblastoma, IHC immunohistochemical staining.

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