Fig. 8: Proteomic analyses of assessing effect exerted by Heimdall neutralization in DI TNC1 astrocytes cell line.

A Heatmap corresponding to shot gun analyses performed on protein cell extracts of DI TNC1 astrocytes incubated with anti-Heimdall (Ac) or stimulated (LPS) or not (CTL) with 200 ng/mL of LPS. String analyses carried out on proteins more abundantly represented after anti-Heimdall treatment (Cluster 1) established the presence of progenitor stem cells factors and proteins involved in cytoskeleton organization. B Venn diagram highlighted specific proteins detected in cell extracts from DI TNC1 astrocytes treated with anti-Heimdall compared to isotype control antibody and no treatment (control).