Fig. 4: Common up-regulated genes identified in DaxxY130A/Y130A and DaxxS226A/S226A are associated with ERVs. | Cell Death & Disease

Fig. 4: Common up-regulated genes identified in DaxxY130A/Y130A and DaxxS226A/S226A are associated with ERVs.

From: The histone chaperone function of Daxx is dispensable for embryonic development

Fig. 4

A–C Venn diagrams of the numbers of upregulated DEGs in brain, lung, and liver of Y130A and S226A tissues compared with wild-type controls. D Average normalized counts of Tmem267 in brain, lung, and liver (mean ± SD). E Schematic representation of the genomic locus of Tmem267 and adjacent ERVs with a zoom-in view. F Expression changes of ten common upregulated DEGs in livers of Y130A and S226A. G Percentage of shared DEGs with associated ERVs, compared with three randomly generated gene lists (mean ± SD) [14].

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