Fig. 1: The cellular components of solid tumors are composed of tumor cells, immune cells, and stromal cells, among which immune cells include: DC, NK, TAM, TAN, MDSC, CD4+T cell/ CD8+T cell/Treg, and Breg. | Cell Death & Disease

Fig. 1: The cellular components of solid tumors are composed of tumor cells, immune cells, and stromal cells, among which immune cells include: DC, NK, TAM, TAN, MDSC, CD4+T cell/ CD8+T cell/Treg, and Breg.

From: Stromal cells in the tumor microenvironment: accomplices of tumor progression?

Fig. 1

Stromal cells include CAF, MSC, CAA, TEC, and PC. These three types of cells establish complex signaling pathways that affect tumor occurrence, tumor progression, and tumor resistance to treatment. Dendritic cell: DC; Natural killer cell: NK; M1/M2 tumor-associated macrophage: M1/M2 TAM; N1/N2 tumor-associated neutrophil: N1/N2 TAN; Myeloid-derived suppressor cell: MDSC; CD4+T lymphocyte/CD8+T lymphocyte/regulatory T cell: CD4+T cell/CD8+T cell/Treg; Regulatory B cell: Breg; Tumor-associated fibroblast: CAF; Mesenchymal stem cell: MSC; Tumor-associated adipocyte: CAA; Tumor endothelial cell: TECs; Pericyte: PC.

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