Fig. 1: MiRNA loss-of-function screening reveals miR-92a-3p as a determinant of lung adenocarcinoma cell sensitivity to cisplatin. | Cell Death & Disease

Fig. 1: MiRNA loss-of-function screening reveals miR-92a-3p as a determinant of lung adenocarcinoma cell sensitivity to cisplatin.

From: miR-92a-3p regulates cisplatin-induced cancer cell death

Fig. 1

A Library of LNA-based miRNA inhibitors against the most expressed miRNAs in A549 was transfected in A549 cell line. Cells were then exposed to cisplatin at 30 µM for 72 h. Viability was measured using the CellTiterGlo assay. B miR-92a-3p (red dot) is the miRNA whose down-regulation is the most associated with cell death after cisplatin exposure at the indicated concentration. n = 2 independent experiments; ***p < 0.001.

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