Fig. 4: β2-AR and EGFR pathways crosstalk. | Cell Death & Disease

Fig. 4: β2-AR and EGFR pathways crosstalk.

From: β2-AR inhibition enhances EGFR antibody efficacy hampering the oxidative stress response machinery

Fig. 4

Western Blot analysis, for assessing the activation levels of the MAPK pathway modulated by β2-AR and the master upstream regulator EGFR. a pMEK/MEK ratio is significantly affected by CTX alone, much more in combination with ICI. b The ERK phosphorylation status followed the same trend observed with pMEK/MEK. (*P ≤ 0.05; **P ≤ 0.01 vs. CTR).

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