Fig. 6: Effects of NRSN2-AS1/PTK2/β-catenin pathway in OC cells. | Cell Death & Disease

Fig. 6: Effects of NRSN2-AS1/PTK2/β-catenin pathway in OC cells.

From: Long non-coding RNA NRSN2-AS1 promotes ovarian cancer progression through targeting PTK2/β-catenin pathway

Fig. 6: Effects of NRSN2-AS1/PTK2/β-catenin pathway in OC cells.The alternative text for this image may have been generated using AI.

OC cells were transfected with EV, OE-NESN2-AS1, OE-NRSN2-AS1+si-PTK2, OE-NRSN2-AS1+si-NC, OE-NRSN2-AS1 + XAV-939 (β-catenin inhibitor, 15 μM), or OE-NRSN2-AS1 + DMSO. A, B Western blot analysis of the expression of PTK2, GSK3Y279/Y216, β-catenin and β-cateninY142, n = 3 for each group. C CCK8 assays were performed to assess cell viability, n = 6. D, E Colony formation assays were done to detect proliferation ability, n = 3. F, G Transwell assays were used to investigate changes in migratory abilities, n = 3. Scale bar: 100 μm. *P < 0.05, **P < 0.01, ***P < 0.001.

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