Fig. 2: Time-dependent histological morphology of the TA muscles in A3R+/+ and A3R−/− mice following CTX-induced injury.

Injection of 50 μl of 12 μM CTX into the TA muscles was used to trigger muscle damage. Representative H&E‐stained cross‐sections of the TA muscles from A3R+/+ and A3R−/− mice before (control) and at days 2, 3, 4, 8, and 22 days after CTX treatment (n = 4). Arrows indicate necrotic areas. Scale bars, 200 μm.