Fig. 1: USP4 was highly expressed in ESCC. | Cell Death & Disease

Fig. 1: USP4 was highly expressed in ESCC.

From: USP4 promotes the proliferation, migration, and invasion of esophageal squamous cell carcinoma by targeting TAK1

Fig. 1

A, B Assessment and quantification of USP4 expression in EC primary tumor and normal tissues from the TCGA database and GSE26886 dataset. C USP4 mRNA levels in tumor and para-cancerous tissue specimens were measured by qRT-PCR (n = 30). D The expression of USP4 protein in ESCC patients was assessed by Western blotting (n = 30). E, F Representative images and quantitation of USP4 expression in ESCC (n = 178) and para-cancerous (n = 40) tissues. G Kaplan‒Meier analysis of the overall survival rate in ESCC patients based on USP4 expression. H Western blotting analysis of USP4 protein expression in ESCC (KYSE150, EC109, KYSE140, KYSE450, KYSE180, and TE-1) and human immortalized esophageal epithelial (Het-1A) cells. *P < 0.05, ***P < 0.001.

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