Fig. 4: Brca2R2971Q mutant mice have normal survival and Brca2RQ/KO mice are mildly sensitive to radiation. | Cell Death & Disease

Fig. 4: Brca2R2971Q mutant mice have normal survival and Brca2RQ/KO mice are mildly sensitive to radiation.

From: Characterization of BRCA2 R3052Q variant in mice supports its functional impact as a low-risk variant

Fig. 4

A Kaplan–Meier survival curve for 750 days of mice of indicated genotypes (n for each genotype is mentioned in the parentheses, Log-rank Mantel–Cox test). B Kaplan–Meier survival curve of mice after 7 Gy IR, mice monitored for 250 days post radiation. RQ/KO mice started to die early showing mild sensitivity to radiation as compared to all other genotypes (n = 10 for each genotype, Log-rank Mantel–Cox test).

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