Fig. 6: The expression of USP27X in BC tissues is positively correlated with the levels of CBX2.
From: Phosphorylation of USP27X by GSK3β maintains the stability and oncogenic functions of CBX2
A IB detection of USP27X and CBX2 in BC specimens. B Correlation analysis of USP27X and CBX2 in BC tissues. Statistical analyses were performed with the χ2 test. The Pearson r indicates correlation coefficient. C Representative images of immunohistochemical staining of USP27X and CBX2 on tissue microarray of BC specimens (n = 132). Scale bar, 100 μm, 500 μm. D Relative CBX2 score = CBX2 protein expression/ Internal reference protein expression (Vinculin). Relative USP27X score = USP27X protein expression/ Internal reference protein expression (Vinculin). Data of IHC were analyzed using Pearson correlation by GraphPad Prism (8.3). E, F Kaplan–Meier curves showing overall survival of BC patients divided based on USP27X (E) and CBX2 expression (F) by GraphPad Prism (8.3). For all panels, data are representative results of three independent experiments.
