Fig. 5: The cellular interaction network of AEG TME. | Cell Death & Disease

Fig. 5: The cellular interaction network of AEG TME.

From: Comparative single-cell analysis reveals heterogeneous immune landscapes in adenocarcinoma of the esophagogastric junction and gastric adenocarcinoma

Fig. 5: The cellular interaction network of AEG TME.

A Connection graphs showing each major cell type as a source to interact with the other cell types. B Connection graphs showing the cellular interactions among major cell types within the TME of either AEG or GAC. C Dot plot showing the co-inhibitory, co-stimulatory, and chemokine interactions between CAFs and T cells. D Dot plot showing the interactions of TGFβ signaling between CAFs to malignant cells. E Expression of FGF ligands and receptors among major cell types. F The differential expression of FGF ligands in malignant cells between AEG and GAC tumors. G Connection graphs showing the intensity of FGF-FGFR interactions in AEG and GAC tumors.

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