Fig. 4: ZNF674-AS1 promotes neuroblastoma cell proliferation. | Cell Death & Disease

Fig. 4: ZNF674-AS1 promotes neuroblastoma cell proliferation.

From: LncRNA ZNF674-AS1 drives cell growth and inhibits cisplatin-induced pyroptosis via up-regulating CA9 in neuroblastoma

Fig. 4

A, B The growth curves of ZNF674-AS1-overexpressing (A) and ZNF674-AS1 KD (B) stable SK-N-BE(2) (left) and SH-SY5Y (right) cells were assessed by MTT assays. C–E Representative micrographs (C), colony numbers (D), and colony area (E) quantifications for ZNF674-AS1-overexpressing stable SK-N-BE(2) (upper) and SH-SY5Y (below) cells. F–H Representative micrographs (F), colony numbers (G), and colony area (H) quantifications for ZNF674-AS1-overexpressing stable SK-N-BE(2) (upper) and SH-SY5Y (below) cells. I, J Representative immunofluorescence images (left) and average Edu positive rates (right) of ZNF674-AS1 KD SK-N-BE(2) (I) and SH-SY5Y (J) cells were presented by Edu incorporation assays. Scale bar, 50 μm. Data are derived from three independent experiments and presented as mean ± SD in the bar graphs. Values of controls were normalized to 1 (A, B). * P < 0.05; ** P < 0.01.

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