Fig. 4: GITRL depletion in liver progenitor cells decreased the proportions of CD8⁺ lymphocytes and GITR⁺CD8⁺ lymphocytes.

A Representative flow cytometry images and statistical quantification of the proportion of GITR⁺ cells among the liver-infiltrating CD45⁺CD3 ^̶ cells and CD45⁺CD3⁺ cells. B Representative flow cytometry images of the proportion of CD4⁺GITR⁺ cells among the liver-infiltrating CD45⁺CD3⁺ lymphocytes. Statistical quantification of the percentage of CD4⁺ cells among the CD45⁺CD3⁺ cells and GITR⁺ cells among CD45⁺CD3⁺CD4⁺ cells. C Representative flow cytometry images of the proportion of CD8⁺GITR⁺ cells among the liver-infiltrating CD45⁺CD3⁺ lymphocytes. Statistical quantification of the percentage of CD8⁺ cells among the CD45⁺CD3⁺ cells and GITR⁺ cells among CD45⁺CD3⁺CD8⁺ cells.