Fig. 1: Single-cell transcriptome analysis of human GIST TME. | Cell Death & Disease

Fig. 1: Single-cell transcriptome analysis of human GIST TME.

From: Deciphering the tumor immune microenvironment of imatinib-resistance in advanced gastrointestinal stromal tumors at single-cell resolution

Fig. 1: Single-cell transcriptome analysis of human GIST TME.

a Overview of the study design. b UMAP plot of all cells from nine samples (five imatinib sensitive and four imatinib resistant) showing the composition of different cell types in human GIST TME. c Fraction of cells (y-axis) from each patient sample (x-axis) color-coded for cell type. d Dot plot showing marker gene expression for different cell types. EC endothelial cell, SMC smooth muscle cell, DC idendritic cell, NK natural killer, UMAP uniform manifold approximation and projection, mIHC multicolor immunofluorescence.

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