Fig. 4: Akt/mTOR pathway was inactivated in Nectin-4-MMAE-treated nectin-4 positive bladder cancer cells. | Cell Death & Disease

Fig. 4: Akt/mTOR pathway was inactivated in Nectin-4-MMAE-treated nectin-4 positive bladder cancer cells.

From: A potential strategy for bladder cancer treatment: inhibiting autophagy to enhance antitumor effects of Nectin-4-MMAE

Fig. 4: Akt/mTOR pathway was inactivated in Nectin-4-MMAE-treated nectin-4 positive bladder cancer cells.

A, C Western blot analysis for the AKT/mTOR pathway showed the total protein levels and phosphorylation levels of Akt, mTOR, P70S6K, 4EBP1 in HT1376 and SW780 treated with Nectin-4-MMAE for the indicated time. B, D The quantification of p-Akt, p-mTOR, p-P70S6K, p-4EBP1 normalized by total Akt, mTOR, P70S6, and 4EBP1 in A, C.

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