Fig. 4: ANXA2 regulates the malignant biological behavior of esophageal cancer cells. | Cell Death & Disease

Fig. 4: ANXA2 regulates the malignant biological behavior of esophageal cancer cells.

From: Annexin A2 combined with TTK accelerates esophageal cancer progression via the Akt/mTOR signaling pathway

Fig. 4: ANXA2 regulates the malignant biological behavior of esophageal cancer cells.The alternative text for this image may have been generated using AI.

A Wound healing assay was used to evaluate the migration in the ANXA2 knockdown group and control group. B, C Transwell assay was employed to study the migration and invasion ability of two kinds of ESCC cells after ANXA2 knockdown. D The cell viability of the control group and si-ANXA2 group was determined by CCK8 assay. E, F The colony formation assay was carried out to clarify the proliferation ability of ESCC cells in the control group and AXNA2 knockdown group. G Wound healing assay was employed to testify the migration ability of ANXA2 overexpressed cells. H, I Changes of cell migration and invasion ability after ANXA2 overexpression were detected by transwell assay. J CCK8 assay was used to detect the cell viability after ANXA2 overexpression. K, L Colony formation was used to evaluate the effect of ANXA2 overexpression on cell proliferation. *, **, and ***, represent P < 0.05, P < 0.01, and P < 0.001, respectively.

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