Fig. 7: AXNA2 partially relies on TTK to promote ESCC development.

A Protein changes in different treatment groups were detected by Western blot. B–D The colony formation and CCK8 assay were used to detect the rescue effect of TTK overexpression on ANXA2 deficiency. (E, F) Wound healing and transwell assay explored the migration and invasion ability of ESCC in different treatment groups. *, **, and ***, represent P < 0.05, P < 0.01, and P < 0.001, respectively.