Fig. 7: Knocking down HNRNPC inhibited tumor growth in vivo. | Cell Death & Disease

Fig. 7: Knocking down HNRNPC inhibited tumor growth in vivo.

From: The m6A reader HNRNPC promotes glioma progression by enhancing the stability of IRAK1 mRNA through the MAPK pathway

Fig. 7

A Subcutaneous tumor transplantation in NOD-SCID mice using U87 cells with HNRNPC-KD or an empty vector (n = 7, left). B Growth curve of the tumors in the HNRNPC-KD and vector groups (right). Tumor volume was calculated using the formula V = ab2/2, where a and b are the tumor length and width, respectively. C Comparison of the tumor volume and weight between the HNRNPC-KD and vector groups. D Hematoxylin and eosin and IHC analyses of HNRNPC and IRAK1 expression in the HNRNPC-KD and vector groups. The n number represents n biologically independent experiments in each group. ***p < 0.001.

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