Fig. 3: CAF-secreted TGFbeta activates TGILR expression in gastric tumor cells. | Cell Death & Disease

Fig. 3: CAF-secreted TGFbeta activates TGILR expression in gastric tumor cells.

From: A novel TGFbeta/TGILR axis mediates crosstalk between cancer-associated fibroblasts and tumor cells to drive gastric cancer progression

Fig. 3

a, b Western blotting assays showed that mature TGFbeta protein levels in CAFs were higher than those in NF from the same donor. c Quantitative RT-PCR assay showed that TGILR expression was higher in CAF than that in NF from the same donor. d Schematic diagram of cell co-culture experiments in different groups. e, f The ELISA assay showed that the content of TGFbeta in the medium co-cultured with CAF and GC cells was significantly higher than that in the medium co-cultured with NF and GC cells. g, h Quantitative RT-PCR assays showed that TGILR expression in GC cells co-cultured with CAF was significantly higher than that in GC cells co-cultured with NF. **, P < 0.01.

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