Fig. 4: TGILR overexpression was clinically correlated with lymph node metastasis and poor survival. | Cell Death & Disease

Fig. 4: TGILR overexpression was clinically correlated with lymph node metastasis and poor survival.

From: A novel TGFbeta/TGILR axis mediates crosstalk between cancer-associated fibroblasts and tumor cells to drive gastric cancer progression

Fig. 4

a, b TGFB1 and TGILR were both significantly upregulated in GC. c The correlation of TGILR expression and clinical characteristics was analyzed in GC patients (n = 373) from the TCGA cohort. The sex differences in the expression level of TGILR in GC. d The expression levels of TGILR in GC patients with different pathologic stages. e–g The expression differences of TGILR in GC patients with different TNM stages. h–j GC patients with higher expression of TGILR possessed shorter overall survival (OVS), disease-specific survival (DSS), and progression-free interval (PFI) in GC. k Cox regression analysis showed that TGILR was an independent prognostic factor for OVS in GC.

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