Fig. 4: Kat2a enhanced ferroptosis of NMVCs under basal and HG conditions.

A The cell death of NMVCs was investigated (N = 3 independent experiments). B The level of labile iron in NMVCs was measured (N = 3 independent experiments). C The level of lipid ROS in the NMVCs (N = 3 independent experiments). D MDA level in NMVCs (N = 3 independent experiments). E, F GSH and GSH/GSSG levels in NMVCs (N = 3 independent experiments). Significance tested using One-way ANOVA. Statistical significance is shown as *p < 0.05, **p < 0.01, ***p < 0.001.