Table 1 Top 10 differentially expressed genes (up and down) following HIBCH knockdown in LNCaP PCa cells.
From: Targeting valine catabolism to inhibit metabolic reprogramming in prostate cancer
Gene (up) | Log (FC) | Adj. P val | Ensembl99 ID | Gene (Down) | Log (FC) | Adj. P val | Ensembl99 ID |
|---|---|---|---|---|---|---|---|
OR51E1 | 12.29 | 2.09E-18 | ENSG00000180785 | HIBCH | −37.48 | 3.11E-65 | ENSG00000198130 |
PLA2G2A | 8.63 | 9.28E-52 | ENSG00000188257 | UGT2B11 | −19.11 | 1.15E-79 | ENSG00000213759 |
LRRN1 | 7.89 | 2.50E-36 | ENSG00000175928 | UGT2B28 | −13.87 | 1.01E-18 | ENSG00000135226 |
LCN2 | 7.45 | 1.95E-05 | ENSG00000148346 | SIPA1L2 | −9.69 | 1.41E-63 | ENSG00000116991 |
SYT4 | 6.27 | 2.04E-37 | ENSG00000132872 | ITGA1 | −6.78 | 4.41E-10 | ENSG00000213949 |
CRYAB | 5.95 | 2.25E-04 | ENSG00000109846 | F5 | −6.46 | 1.23E-25 | ENSG00000198734 |
HIPK3 | 5.25 | 1.39E-22 | ENSG00000110422 | AGR2 | −6.21 | 1.22E-12 | ENSG00000106541 |
PXYLP1 | 5.13 | 7.83E-05 | ENSG00000155893 | FAR2P3 | −6.20 | 8.07E-04 | ENSG00000240253 |
PRSS1 | 5.10 | 2.78E-03 | ENSG00000204983 | ZNF812P | −6.15 | 4.36E-16 | ENSG00000224689 |
SLC7A2 | 4.87 | 1.77E-15 | ENSG00000003989 | ODAM | −5.87 | 5.88E-04 | ENSG00000109205 |
