Fig. 6: The effect of LTB4 on CD8+ T cells. | Cell Death & Disease

Fig. 6: The effect of LTB4 on CD8+ T cells.

From: Elucidating the role of S100A10 in CD8+ T cell exhaustion and HCC immune escape via the cPLA2 and 5-LOX axis

Fig. 6

A HPLC analysis of extracellular LTB4 levels in MHCC97-L cells. B Flow cytometry analysis of the expression levels of Ki67, CD69, IL-2, IFN-γ, and TNF-α in CD8+ T cells from different groups. C Transmission electron microscopy observation of the number of mitochondria in CD8+ T cells from different groups, with red arrows indicating mitochondria (scale bar = 5 μm). D RT-qPCR analysis of mtRNA copy numbers in CD8+ T cells from different groups. E Transmission electron microscopy observation of the number and total length of mitochondrial cristae in CD8+ T cells from different groups, with red arrows indicating mitochondrial cristae (scale bar = 500 nm). F Flow cytometry analysis of mitochondrial mass and membrane potential in CD8+ T cells from different groups. Cell experiments were repeated three times. * represents comparison between two groups, p < 0.05, p < 0.01, **p < 0.001.

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