Fig. 1: HMGA1 is highly expressed in esophageal cancer. | Cell Death & Disease

Fig. 1: HMGA1 is highly expressed in esophageal cancer.

From: HMGA1 promotes the progression of esophageal squamous cell carcinoma by elevating TKT-mediated upregulation of pentose phosphate pathway

Fig. 1

A–C The tSNE map showed the distribution of epithelial cells from normal (N) and tumor (T) in esophageal tissue in ESCC patients from scRNA-seq data in the GEO database (GSE188900 dataset). HMGA1 was mainly expressed in epithelial cells from tumor (C). D HMGA1 expression in ESCC (n = 28) and paired paracancerous (n = 10) samples in the GEO database (GSE45670 dataset). E The TCGA database analyzes the expression of HMGA1 at normal and tumor tissues of different stages of ESCCs. F, G Representative IHC staining of HMGA1 in paired ESCC tissues. Scale bars: 50 μm. H, I Representative IHC staining of HMGA1 in 4NQO-induced esophageal tumor tissue and H2O-treated normal esophageal tissue. Scale bars: 50 μm.

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