Table 1 Sterile acute inflammatory conditions and their impact on DNases.
Disease/condition | Species | Effect | References | |
|---|---|---|---|---|
Blood levels | Activity | |||
Acute kidney injury | Human | ↑ DNA | = DNase activity | [144] |
Acute liver failure | Mouse | ↑ DNA | ↓ DNase activity | [145] |
Acute thrombotic microangiopathy | Human | ↑ DNA | ↓ DNase activity | [146] |
Burn | Human | ↑ DNA | ↓ DNase activity | [22] |
↑ actin | ||||
= DNase protein levels | ||||
Mouse | ↑ DNA | - | [147] | |
↑ DNase protein levels | ||||
Stroke | Human | ↑ DNA | ↓ DNase activity | [148] |
Trauma | Human | ↑ DNA | ↓ DNase activity | |
↑ actin | ||||
↑ DNase protein levels | ||||
