Table 3 Inflammatory conditions and the impact on the actin-scavenger system.
Disease/condition | Species | Levels in | References | |
|---|---|---|---|---|
Blood | Other body fluids | |||
Acute liver failure | Human | ↓ DBP | - | |
Acute lung injury | Mouse | ↓ gelsolin | - | [161] |
Bronchopulmonary dysplasia | Mouse | - | BALF | [103] |
↑ F-actin | ||||
↑ F-actin/gelsolin ratio | ||||
Human | - | ↑ F-actin/gelsolin ratio | ||
Burn | Human | ↓ gelsolin | Burn wound fluid | |
↓ DBP | Detection of actin, gelsolin and DBP | |||
↑ actin |  | |||
Multiple sclerosis | Human | ↓ gelsolin | Cerebrospinal fluid | [98] |
= DBP | = gelsolin | |||
| Â | = DBP | |||
Rheumatoid arthritis | Human | ↓ gelsolin | Synovial fluid | [48] |
↑ actin | Detection of actin and gelsolin | |||
Sepsis | Mouse | ↓ gelsolin | - | [102] |
↑ actin | ||||
Human | ↓ gelsolin | - | [47] | |
↑ actin | ||||
Traumatic brain injury | Human | ↓ gelsolin | - | [18] |
↓ DBP | ||||
↑ G-actin | ||||
Trauma | Human | ↓ gelsolin | - | |
↓ DBP | ||||
