Fig. 3: HIF1A-AS2 promotes the proliferation, invasion, and metastasis of CRC cells in vivo.

A, B Images of subcutaneous tumors, Volumes and weights of subcutaneous tumors. C Representative IHC images showing the expression of Ki67, E-cadherin, and N-cadherin in subcutaneous tumors in different groups. Scale bar = 20 μm. D Representative photographs of bioimaging. E Pictures of mouse liver specimen. F Kaplan–Meier curve comparing the OS between the sh-NC group and sh-HIF1A-AS2 group. G Representative photographs of bioimaging. H Pictures of mouse liver specimen. I Kaplan–Meier curve comparing the OS between the control group and HIF1A-AS2 group. *P < 0.05; **P < 0.01; ***P < 0.001; ns no significance.