Fig. 4: DH disturbed mitochondria homeostasis. | Cell Death & Disease

Fig. 4: DH disturbed mitochondria homeostasis.

From: Dronedarone hydrochloride (DH) induces pancreatic cancer cell death by triggering mtDNA-mediated pyroptosis

Fig. 4

A Representative images of DCFH-FA staining result in PANC-1 cells with or without DH treatment. White or Green, DCFH positive stained area. Scale bar, 200 μm. B Quantification of DCFH-FA positive staining area in images in Fig. 4A. n = 3. C Representative images of MitoSox staining results in PANC-1 cells with or without DH treatment. Scale bar, 50 μm. Red, MitoSox positive stained area. D Quantification of MitoSox positive staining area in images in Fig. 4C. n = 3. E Representative immunofluorescent images of Tom20 staining results in PANC-1 cells with or without DH treatment. Scale bar, 25 μm. Red, Tom20; Blue, DAPI. Data was shown as mean ± SD. Unpaired t-test was used. **p < 0.01; ***p < 0.001.

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