Fig. 5: Clinical and survival analysis of METTL1 in various tumors. | Cell Death & Disease

Fig. 5: Clinical and survival analysis of METTL1 in various tumors.

From: A N7-methylguanosine modified circular RNA, circIPP2A2, promotes malignant behaviors in hepatocellular carcinoma by serving as a scaffold in modulating the Hornerin/PI3K/AKT/GSK3β axis

Fig. 5: Clinical and survival analysis of METTL1 in various tumors.

a, b A pan-cancer survival analysis was performed to determine the expression of METTL1 in various cancers. c The association between METTL1 and clinical outcome was measured using Kaplan–Meier curves in patients with HCC. d Violin plot depicted the correlation between METTL1 expression and tumor postoperative pathological grade in HCC. e qPCR assay was used to measure the expression of METTL1 in 16 pairs of HCC and corresponding normal liver tissues. f, g Western blotting and IHC were performed to assess the protein level of METTL1 in HCC and corresponding normal liver tissues. ns, not significant; *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

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