Fig. 6: SQLE overexpression promoted cholesterol metabolism. | Cell Death & Disease

Fig. 6: SQLE overexpression promoted cholesterol metabolism.

From: Stabilization of SQLE mRNA by WTAP/FTO/IGF2BP3-dependent manner in HGSOC: implications for metabolism, stemness, and progression

Fig. 6

a Heatmap of differentially expressed metabolites (DEMs). b Correlation analysis between differential metabolites. c These DEMs were involved in many metabolism pathways. d The chord diagram displayed the correspondence of genes and pathways. The VIP values of shared DEMs were shown in a histogram. e The DEMs were involved in cholesterol production, cholesterol metabolism, and glutathione metabolism. f SQLE overexpression increased the level of total cholesterol. *p < 0.05, **p < 0.01, and ***p < 0.001.

Back to article page