Table 2 Univariate Cox regression analysis was conducted to examine the correlation between SIRT7 and RND3 expression and the OS of patients with bladder cancer.
From: Mechanistic insights into SIRT7 and EZH2 regulation of cisplatin resistance in bladder cancer cells
Characteristics | OS | |
|---|---|---|
| Â | HR (95%CI) | P value |
Age (year) | ||
 ≥63 VS <63 | 1.389(0.806–2.393) | 0.237 |
Gender | ||
 Male VS Female | 1.806(0.771–4.230) | 0.173 |
BMI (kg/m2) | Â | Â |
 ≥24 VS <24 | 1.293(0.753–2.220) | 0.351 |
Smoking history | ||
 Yes VS No | 1.224(0.692–2.165) | 0.448 |
T stage | ||
 T3/T4 VS T2 | 5.628(2.974–10.651) | <0.001 |
Lymph node metastasis | ||
 N1/N2 VS N0/Nx | 4.297(2.441–7.556) | <0.001 |
Vascular invasion | ||
 Yes VS No | 4.485(2.393–8.405) | <0.001 |
Histological variant | ||
 Yes VS No | 1.510(0.733–3.109) | 0.263 |
Chemotherapy protocol | ||
 Cisplatin VS Carboplatin | 1.626(0.395–6.682) | 0.501 |
SIRT7 expression | ||
 High VS Low | 4.027(1.808–8.966) | <0.001 |
RND3 expression | ||
 High VS Low | 0.327(0.154–0.696) | 0.004 |
