Fig. 3: Inhibition of PLIN1 enhances proliferation and invasion of glioma. | Cell Death & Disease

Fig. 3: Inhibition of PLIN1 enhances proliferation and invasion of glioma.

From: PLIN1 suppresses glioma progression through regulating lipid metabolism

Fig. 3: Inhibition of PLIN1 enhances proliferation and invasion of glioma.The alternative text for this image may have been generated using AI.

A Inhibition of PLIN1 in glioma cells was confirmed by qRT-PCR. B Inhibition of PLIN1 in glioma cells was confirmed by western blotting. And the western blotting bands were quantified with ImageJ software (Right). C CCK-8 assay after PLIN1 inhibition. D Colony formation assay after PLIN1 inhibition. Left: represent image of colony formation assay; Right: colony formation number was quantified by ImageJ software. E Transwell assay after PLIN1 inhibition. Left: represent image of Transwell assay; Right: invasive cell number was quantified. F Glioma xenograft models were constructed with SHG-44-PLIN1 knockdown cell or non-treated SHG-44 cell as control. Left: represent image of xenograft tumors. Right: the tumor weights were measured. G The expression of PLIN1 and Ki67 in xenograft tumors were detected by IHC staining. *P < 0.05, **P < 0.01. The experiment was repeated three times independently.

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