Fig. 5: Irisin relieves oxidative stress via UCP2.

A, B Detection of mtROS production in N2a cells after treatment, performed using MitoSOX staining and flow cytometry analysis. C–F Measurement of MDA content, GSH/GSSH ratio, and CAT and T-SOD activities in N2a cells. The data are presented as the means ± SDs (n = 6), *P < 0.05; **P < 0.01; ***P < 0.001.