Table 1 Clinicopathologic feature of endometrial cancer with or without diabetes mellitus.
Characteristics | EC without DM (n = 462) | EC with DM (n = 80) | p Value |
|---|---|---|---|
Age at diagnosis, median (IQR) | 53 (49, 58) | 59 (56, 62.25) | <0.001 |
Menopausal status, n (%) | <0.001 | ||
No | 246 (53.2%) | 65 (81.2%) | |
Yes | 216 (46.8%) | 15 (18.8%) | |
BMI, median (IQR) | 24.07 (21.965, 26.497) | 25.242 (22.885, 27.033) | 0.031 |
Hypertension | <0.001 | ||
No | 344 (74%) | 28 (35%) | |
Yes | 118 (26%) | 52 (65%) | |
Total Cholesterol, n (%) | <0.001 | ||
≥5.2 (mmol/L) | 314 (68%) | 37 (46.2%) | |
<5.2 (mmol/L) | 148 (32%) | 43 (53.8%) | |
Triglyceride, n (%) | 0.006 | ||
<1.7 (mmol/L) | 320 (69%) | 43 (54%) | |
≥1.7 (mmol/L) | 142 (31%) | 37 (46%) | |
CA125 (U/ml), median (IQR) | 20.8 (14, 40.9) | 23.2 (12.2, 38.3) | 0.855 |
ER expression, n (%) | 0.222 | ||
Low | 197 (43.3%) | 28 (35.9%) | |
High | 258 (56.7%) | 50 (64.1%) | |
PR expression, n (%) | 0.404 | ||
Low | 198 (43.5%) | 30 (38.5%) | |
High | 257 (56.5%) | 48 (61.5%) | |
FIGO stage, n (%) | 0.188 | ||
I–II | 71 (15.4%) | 17 (21.2%) | |
III–IV | 391 (84.6%) | 63 (78.8%) | |
CSI, n (%) | 0.579 | ||
No | 376 (81.4%) | 63 (78.8%) | |
Yes | 86 (18.6%) | 17 (21.2%) | |
MI, n (%) | <0.001 | ||
No | 353 (76.4%) | 45 (56.2%) | |
Yes | 109 (23.6%) | 35 (43.8%) | |
LVSI, n (%) | 0.821 | ||
No | 394 (85.3%) | 69 (86.2%) | |
Yes | 68 (14.7%) | 11 (13.8%) | |
LNM, n (%) | 0.795 | ||
No | 420 (90.9%) | 72 (90%) | |
Yes | 42 (9.1%) | 8 (10%) |
