Fig. 3: MCI protects cells against ferroptosis in mitochondria. | Cell Death & Disease

Fig. 3: MCI protects cells against ferroptosis in mitochondria.

From: Inhibition of mitochondrial complex I induces mitochondrial ferroptosis by regulating CoQH2 levels in cancer

Fig. 3: MCI protects cells against ferroptosis in mitochondria.The alternative text for this image may have been generated using AI.

Lipid peroxidation levels in NDI1 overexpression Huh7 or NCI-H23 cells treated with ROT (50 μM) (a) or IACS (50 μM) (b). c Lipid peroxidation levels in NDI1 overexpression Huh7 or NCI-H23 cells treated with RSL3 (0.5 μM) or ML162 (0.5 μM) for 1.5 h. d Mitochondrial lipid peroxidation in NDI1 overexpression Huh7 or NCI-H23 cells treated with RSL3 (0.5 μM) or ML162 (0.5 μM) for 1.5 h. e Mitochondrial lipid peroxidation in NDI1 overexpression Huh7 or NCI-H23 cells 24 h after exposure to 10 Gy of IR.

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