Fig. 1: Morphological and phenotypic characteristics of cultured CTCs. | Cell Death & Disease

Fig. 1: Morphological and phenotypic characteristics of cultured CTCs.

From: Gastroesophageal circulating tumor cell crosstalk with peripheral immune system guides CTC survival and proliferation

Fig. 1

a Representative images of the four CTC-derived cell lines. Tumoroid structures can be noticed in all cell lines (black arrows). 5x (upper) and 10x (lower) magnification, phase contrast, scalebar 100 µm. b FACS analysis of EpCAM-positive cell populations (red curve) and negative control (cyan curve) The percentage of EpCAM+ cells is indicated. c Histological characterization of CTC-derived cell lines. Panels show cellular staining with hematoxylin/eosin (H&E), cytokeratin-7 (K7), cytokeratin-20 (K20), caudal type homeobox 2 (CDX2) and tumor protein p63.

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