Table 2 Association of SERPINA3 concentrations with NIHSS scores at blood collection.

From: SERPINA3 predicts long-term neurological outcomes and mortality in patients with intracerebral hemorrhage

 

Adjusting for the time from hemorrhage to blood collection

Adjusting for the time from hemorrhage to blood collection, age at blood collection, sex, current smoking, hypertension, cerebrovascular disease, and diabetes

Variable types

N

β (95%CI)

P-value

β (95%CI)

P-value

 Overall

250

1.34 (0.97, 1.71)

<0.001

1.21 (0.84, 1.58)

<0.001

Hemorrhage location

 No

220

1.3 (0.93, 1.67)

<0.001

1.22 (0.84, 1.60)

<0.001

 Yes

30

1.77 (0.08, 3.45)

0.040

0.35 (−1.68, 2.38)

0.723

Ventricular extension

 No

182

1.24 (0.83, 1.65)

0.001

1.12 (0.70, 1.54)

<0.001

 Yes

68

1.24 (0.83, 1.65)

0.001

1.12 (0.70, 1.54)

0.002

Surgery

 No

140

0.73 (0.22, 1.23)

0.005

0.6 (0.09, 1.11)

0.022

 Yes

110

0.9 (0.36, 1.44)

0.001

0.88 (0.32, 1.44)

0.002

  1. β regression coefficient; CI confidence interval. The β values, 95% CIs, and p-values were obtained from the linear regression models. β values were interpreted as the change in mean NIHSS scores for each fold of SERPINA3 concentration. NIHSS National Institutes of Health Stroke Scale.
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