Fig. 1: No neuronal loss of mdDA neurons in the absence of Pitx3 at E14,5 and E16,5. | Cell Death & Disease

Fig. 1: No neuronal loss of mdDA neurons in the absence of Pitx3 at E14,5 and E16,5.

From: The absence of Pitx3 results in postnatal loss of dopamine neurons and is associated with an increase in the pro-apoptotic Bcl2 factor Noxa and cleaved caspase 3

Fig. 1

(Left) Schematic representation of developing mdDA neuronal pool in sagittal and coronal view. In the coronal view, the segregation between lateral (I and II) and medial is indicated (III and IV) (Right) GFP immunohistochemistry of lateral sections of Pitx3GFP/+ and Pitx3GFP/GFP animals at E14.5 and E16.5.

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