Fig. 6: Cleaved caspase 3 is increased in the absence of Pitx3 at P3. | Cell Death & Disease

Fig. 6: Cleaved caspase 3 is increased in the absence of Pitx3 at P3.

From: The absence of Pitx3 results in postnatal loss of dopamine neurons and is associated with an increase in the pro-apoptotic Bcl2 factor Noxa and cleaved caspase 3

Fig. 6

A Immunohistochemistry for GFP and CC3 in different sections from lateral to medial encompassing the mdDA neuronal pool in Pitx3GFP/+ animals. B The same setup as described for A in Pitx3GFP/GFP animals (matching sections with A). C Quantification of GFP/CC3-positive neurons in Pitx3GFP/+ and Pitx3GFP/GFP animals ** p < 0.01, n = 4.

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