Fig. 8: The role of BCAT2 in vivo. | Cell Death & Disease

Fig. 8: The role of BCAT2 in vivo.

From: BCAT2 binding to PCBP1 regulates the PI3K/AKT signaling pathway to inhibit autophagy-related apoptosis and ferroptosis in prostate cancer

Fig. 8

A Different groups of DU145 cells were injected subcutaneously into nude mice. B Tumor weight and C tumor volume were statistically analyzed. D, E Immunohistochemical staining was performed to detect markers of cellular proliferation, autophagy, apoptosis, ferroptosis and p-AKT activity in the tumor of mice. F, G In vivo imaging of different groups of luciferase labeled PCa lung metastasis models, as well as representative lung tissue and hematoxylin-eosin staining. The fluorescence intensity of each model was obtained under the same exposure.

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