Fig. 6: GLI2 and DEC1 co-regulate tumor growth, metastasis, and CDDP sensitively in vivo.
From: GLI2 inhibits cisplatin sensitivity in gastric cancer through DEC1/ZEB1 mediated EMT
A Subcutaneous tumor models (n = 6 mice per group) were established using stable expressed MKN-45 cells combined with CDDP intraperitoneal injection. Tumor weights were analyzed. B Representative H&E images (scale bar: 200 μm) of lung samples from the indicated groups of nude mice. C IHC staining for DEC1 ZEB1, N-cadherin, Vimentin, Snail1, Ki67 expression in xenografts. Scale bars: 50 μm. ***P < 0.001, **P < 0.01, *P < 0.05.
