Table 1 Correlation between GLI2 and clinicopathologic parameters in gastric cancer.
From: GLI2 inhibits cisplatin sensitivity in gastric cancer through DEC1/ZEB1 mediated EMT
Characteristic | Expression of GLI2 | X2-test | p value | ||
|---|---|---|---|---|---|
High | Low | ||||
Gender | Male | 47 | 26 | 0.017 | 0.502 |
Female | 20 | 8 | |||
Age (years) | ≤50 | 57 | 30 | 0.45 | 0.897 |
>50 | 10 | 4 | |||
Pathological | Intestinal | 6 | 3 | 0.04 | 0.98 |
Diffuse | 54 | 27 | |||
Signet ring | 7 | 4 | |||
Differentiation | G1 G2 | 15 | 19 | 11.33 | 0.001 |
G3 | 52 | 15 | |||
Max tumor diameter | >5 cm | 47 | 16 | 5.12 | 0.024 |
≤5 cm | 20 | 18 | |||
T classification | T1 T2 | 12 | 16 | 9.564 | 0.002 |
T3 T4 | 55 | 18 | |||
N classification | Positive | 56 | 18 | 5.598 | 0.018 |
Negative | 11 | 16 | |||
Clinical staging | I II | 35 | 17 | 0.045 | 0.832 |
III IV | 32 | 17 | |||
Cisplatin therapy | Sensitive | 9 | 21 | 4.344 | 0.037 |
Resistant | 17 | 13 | |||