Fig. 5: CDC25A plays a crucial role in melanoma cells.
From: CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy
A The synergistic effects of CDC25 family member expression were analyzed. The left panel shows scatter plots representing the z-scores of the samples, where each point represents a sample. Different colors indicate distinct subgroups and the horizontal/vertical axes correspond to the z-scores of the two genes, respectively. A z-score ≤ 0 indicates low expression, while a z-score > 0 indicates high expression. The right panel shows a Kaplan–Meier survival analysis of melanoma patients based on the expression of CDC25 family members. B The expression levels of mCherry were analyzed in A375 and MUM2B CDC25A-KD cells by flow cytometry. C Western blot assessed the protein level of CDC25A in A375 CDC25A-KD cells. D Representative images of A375 and MUM2B CDC25A-KD cells were shown. Scale bars: 100 μm.
