Table 2 Characteristics of different expression level of MMP1.

From: MMP1-induced NF-κB activation promotes epithelial–mesenchymal transition and sacituzumab govitecan resistance in hormone receptor-positive breast cancer

Characteristics

Low expression of MMP1

High expression of MMP1

P-value

n

543

544

 

Pathologic T stage, n (%)

  

<0.001

 T1&T2

433 (39.9%)

476 (43.9%)

 

 T3&T4

108 (10%)

67 (6.2%)

 

Pathologic N stage, n (%)

  

0.003

 N0

267 (25%)

249 (23.3%)

 

 N1&N2

215 (20.1%)

260 (24.3%)

 

 N3

50 (4.7%)

27 (2.5%)

 

Pathologic M stage, n (%)

  

0.118

 M0

431 (46.6%)

474 (51.2%)

 

 M1

6 (0.6%)

14 (1.5%)

 

Pathologic stage, n (%)

  

0.053

 Stage I

97 (9.1%)

85 (8%)

 

 Stage II

295 (27.8%)

324 (30.5%)

 

 Stage III

133 (12.5%)

111 (10.4%)

 

 Stage IV

5 (0.5%)

13 (1.2%)

 

Histological type, n (%)

  

<0.001

 Infiltrating Lobular Carcinoma

157 (16%)

48 (4.9%)

 

 Infiltrating Ductal Carcinoma

322 (32.8%)

454 (46.3%)

 

 PAM50, n (%)

  

<0.001

 LumA

370 (35.3%)

194 (18.5%)

 

 LumB

82 (7.8%)

124 (11.8%)

 

 Her2

16 (1.5%)

66 (6.3%)

 

 Basal

54 (5.2%)

141 (13.5%)

 

 Age, n (%)

  

0.036

 <= 60

284 (26.1%)

319 (29.3%)

 

 > 60

259 (23.8%)

225 (20.7%)

 

Menopause status, n (%)

  

0.845

 Pre

113 (11.6%)

117 (12%)

 

 Post & Peri

372 (38.1%)

374 (38.3%)