Table 3 COX univariate and multivariate analysis of MMP1 and other characteristics.
Characteristics | Total(N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | ||
MMP1 | 1066 | ||||
Low | 530 | Reference | Reference | ||
High | 536 | 1.771 (1.142–2.748) | 0.011 | 2.034 (1.183–3.498) | 0.010 |
Pathologic stage | 1044 | ||||
Stage I & Stage II | 790 | Reference | Reference | ||
Stage III & Stage IV | 254 | 3.486 (2.253–5.394) | <0.001 | 3.502 (2.157–5.686) | < 0.001 |
ER status | 1019 | ||||
Indeterminate & Positive | 787 | Reference | Reference | ||
Negative | 232 | 1.764 (1.108–2.808) | 0.017 | 1.276 (0.605–2.694) | 0.522 |
PR status | 1018 | ||||
Indeterminate & Positive | 684 | Reference | Reference | ||
Negative | 334 | 1.906 (1.228–2.957) | 0.004 | 1.352 (0.665–2.748) | 0.405 |
HER2 status | 718 | ||||
Indeterminate & Positive | 166 | Reference | |||
Negative | 552 | 0.714 (0.358–1.426) | 0.340 | ||
Histological type | 962 | ||||
Infiltrating Ductal Carcinoma | 762 | Reference | Reference | ||
Infiltrating Lobular Carcinoma | 200 | 0.472 (0.226–0.986) | 0.046 | 0.412 (0.172–0.989) | 0.047 |
Menopause status | 965 | ||||
Pre & Peri | 268 | Reference | |||
Post | 697 | 1.552 (0.867–2.780) | 0.139 | ||
Age | 1066 | ||||
<= 60 | 592 | Reference | Reference | ||
> 60 | 474 | 1.446 (0.942–2.222) | 0.092 | 2.005 (1.212–3.319) | 0.007 |
