Fig. 1: Rap2B positively correlates with increased metastasis and poor prognosis in CRC patients. | Cell Death & Disease

Fig. 1: Rap2B positively correlates with increased metastasis and poor prognosis in CRC patients.

From: Rap2B drives tumorigenesis and progression of colorectal cancer through intestinal cytoskeleton remodeling

Fig. 1: Rap2B positively correlates with increased metastasis and poor prognosis in CRC patients.

A Analysis of Rap2B expression in colon cancer in TCGA database. B, C Representative images and IHC intensity analysis using Rap2B antibody in 179 human colon cancer and 161 adjacent normal colon tissue. The percentages of high Rap2B expression levels correlated with histologic grades (D), tumor sizes (E), LN metastasis (F) and distant metastasis (G) were examined by χ2 test. H High Rap2B expression were correlated with overall survival in 814 colon cancer patients (High Rap2B patients 214, Low Rap2B patients 600) (P = 0.0077, log-rank test). Data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 by 2-tailed unpaired t test.

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