Fig. 1: Overexpression of NDUFS8 correlates with poor prognosis of NSCLC.

The Cancer Genome Atlas (TCGA) lung adenocarcinoma (LUAD) lung squamous cell carcinoma (LUSC) cohort (combining both LUAD and LUSC), TCGA-LUAD cohort and TCGA-LUSC cohort show NDUFS8 expression (RNA-Seq) in NSCLC tissues (“Tumor”), normal lung tissues (“Normal”) (A–C) and also in paired cancer-surrounding normal tissues (D–F). The receiver operating characteristic (ROC) curve results demonstrated the relationship between NDUFS8 overexpression and the potential predictive effect on NSCLC patients’ survival (G–I). The Kaplan-Meier survival analyses show that the association between NDUFS8 expression and the overall survival of NSCLC patients (J–L) and subgroup NSCLC patients (M–R). Transcripts Per Million (TPM), True Positive Rate (TPR) and False Positive Rate (FPR). *P < 0.05. **P < 0.01. ***P < 0.001.