Fig. 4: SIRT3 silencing aggravates adipocytes CM induced inflammatory responses in macrophages. | Cell Death & Disease

Fig. 4: SIRT3 silencing aggravates adipocytes CM induced inflammatory responses in macrophages.

From: Adipocyte-expressed SIRT3 manipulates carnitine pool to orchestrate metabolic reprogramming and polarization of macrophages

Fig. 4

The mRNA expression of Tnf-α (A) Il-6 (B) Il-1β (C) and iNos (D) in BMDMs. The mRNA expression of Mrc1 (E) Mgl2 (F) Arg1 (G) and Chil3 (H) in BMDMs. I The mRNA expression of Mcp-1, Mip-1α, Ccl5, Ccl11 and Cxcl10 in BMDMs. n = 3 independent experiments. Data are expressed as means ± SEM. #P < 0.05, ##p < 0.01, ###p < 0.001, Scramble vs. control; *P < 0.05, **P < 0.01, ***P < 0.001, Scramble vs. SIRT3KD.

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