Fig. 5: Metabolomic profiles of CM from vector and SIRT3OE adipocytes. | Cell Death & Disease

Fig. 5: Metabolomic profiles of CM from vector and SIRT3OE adipocytes.

From: Adipocyte-expressed SIRT3 manipulates carnitine pool to orchestrate metabolic reprogramming and polarization of macrophages

Fig. 5

A PCA analysis of vector and SIRT3OE cells. Each dot represents the technological replicate analysis of samples. B S-plot generated from OPLS-DA. Dot represents metabolites, which are p [1] < -0.05 or > 0.05 and p (corr) [1] < -0.5 or > 0.5 and marked in red dot. (C) Heat maps of significant differentially expressed metabolites. (D) Pathway classifications were selected to plot. n = 6 replicates.

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